Bumetanide for treatment of seizures in neonates

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Bumetanide for treatment of seizures in neonates.

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Combined effect of bumetanide, bromide, and GABAergic agonists: An alternative treatment for intractable seizures

The epilepsies constitute one of the most common serious brain disorders and know no geographic, social, or racial boundaries, occurring in men and women and affecting people of all ages, though more frequently affecting young people in the first two decades of life and people over the age of 60 [1,2]. Worldwide, there are at least 50 million people who have epilepsy, and many of these persons ...

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Bumetanide for neonatal seizures: Based on evidence or enthusiasm?

Seizures in the neonatal period are serious events associated with high morbidity and mortality. A major clinical problem is that neonatal epileptic seizure activity shows only limited response to the commonly used anticonvulsant drugs. Consequently, the optimal treatment of neonatal seizures (NSs) is currently a highly prioritized issue (Silverstein et al., 2008). There is not only a lack of w...

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ژورنال

عنوان ژورنال: The Lancet Neurology

سال: 2015

ISSN: 1474-4422

DOI: 10.1016/s1474-4422(15)70024-4